Gene description for EZR
Gene name ezrin
Gene symbol EZR
Other names/aliases CVIL
CVL
HEL-S-105
VIL2
Species Homo sapiens
 Experiment description of studies that identified EZR in Melanoma cells

1
Experiment ID12
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 15478216   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
AuthorsMears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE
Journal name PROTEOMICS
Publication year2004
SampleMelanoma cells
Sample nameMeWo
SK-MEL-28
Isolation/purification methodsFiltration
Ultracentrifugation
Sucrose density gradient
Flotation density1.13-1.20 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [4700 Proteomics Analyzer]
Western blotting
EV-TRACK -

2
Experiment ID618
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameM14
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

3
Experiment ID986
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25261472   
OrganismHomo sapiens
Experiment descriptionComplex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.
AuthorsLiang Y, Eng WS, Colquhoun DR, Dinglasan RR, Graham DR, Mahal LK.
Journal name J Biol Chem.
Publication year2014
SampleMelanoma cells
Sample nameSK-MEL-5
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140188: EV-METRIC:22%

<